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The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation.
Pastori, Chiara; Kapranov, Philipp; Penas, Clara; Peschansky, Veronica; Volmar, Claude-Henry; Sarkaria, Jann N; Bregy, Amade; Komotar, Ricardo; St Laurent, Georges; Ayad, Nagi G; Wahlestedt, Claes.
Affiliation
  • Pastori C; Center for Therapeutic Innovation and Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, FL 33136;
  • Kapranov P; Institute of Genomics, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, China; St. Laurent Institute, Woburn, MA 01801;
  • Penas C; Center for Therapeutic Innovation and Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, FL 33136;
  • Peschansky V; Center for Therapeutic Innovation and Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, FL 33136;
  • Volmar CH; Center for Therapeutic Innovation and Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, FL 33136;
  • Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905;
  • Bregy A; Department of Neurosurgery, University of Miami, Miami, FL 33136.
  • Komotar R; Department of Neurosurgery, University of Miami, Miami, FL 33136.
  • St Laurent G; St. Laurent Institute, Woburn, MA 01801;
  • Ayad NG; Center for Therapeutic Innovation and Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, FL 33136; cwahlestedt@med.miami.edu NAyad@med.miami.edu.
  • Wahlestedt C; Center for Therapeutic Innovation and Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, FL 33136; cwahlestedt@med.miami.edu NAyad@med.miami.edu.
Proc Natl Acad Sci U S A ; 112(27): 8326-31, 2015 Jul 07.
Article in En | MEDLINE | ID: mdl-26111795
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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Brain Neoplasms / Nuclear Proteins / Glioblastoma / Cell Proliferation / RNA, Long Noncoding Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Brain Neoplasms / Nuclear Proteins / Glioblastoma / Cell Proliferation / RNA, Long Noncoding Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Type: Article