Efficient high-throughput biological process characterization: Definitive screening design with the ambr250 bioreactor system.

Tai, Mitchell; Ly, Amanda; Leung, Inne; Nayar, Gautam

Tai, Mitchell; Ly, Amanda; Leung, Inne; Nayar, Gautam.

Affiliation

Tai M; Biologics Process Development, Bristol-Myers Squibb, Seattle, WA.
Ly A; Biologics Process Development, Bristol-Myers Squibb, Seattle, WA.
Leung I; Biologics Process Development, Bristol-Myers Squibb, Seattle, WA.
Nayar G; Biologics Process Development, Bristol-Myers Squibb, Seattle, WA.

Biotechnol Prog ; 31(5): 1388-95, 2015.

Article in En | MEDLINE | ID: mdl-26138048

Subject(s)

Bioreactors; Fermentation; High-Throughput Screening Assays/methods; Escherichia coli/metabolism; Recombinant Proteins/biosynthesis; Workflow

Key words

Escherichia coli fermentation; ambr250; definitive screening design; design of experiment; high-throughput; process characterization; process development; quality by design

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Full text: 1 Database: MEDLINE Main subject: Bioreactors / High-Throughput Screening Assays / Fermentation Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Language: En Journal: Biotechnol Prog Journal subject: BIOTECNOLOGIA Year: 2015 Type: Article

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