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An in vivo genetic reversion highlights the crucial role of Myb-Like, SWIRM, and MPN domains 1 (MYSM1) in human hematopoiesis and lymphocyte differentiation.
Le Guen, Tangui; Touzot, Fabien; André-Schmutz, Isabelle; Lagresle-Peyrou, Chantal; France, Benoit; Kermasson, Laetitia; Lambert, Nathalie; Picard, Capucine; Nitschke, Patrick; Carpentier, Wassila; Bole-Feysot, Christine; Lim, Annick; Cavazzana, Marina; Callebaut, Isabelle; Soulier, Jean; Jabado, Nada; Fischer, Alain; de Villartay, Jean-Pierre; Revy, Patrick.
Affiliation
  • Le Guen T; INSERM UMR 1163, Laboratory of Genome Dynamics in the Immune System, Paris, France; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Touzot F; INSERM UMR 1163, Laboratory of Genome Dynamics in the Immune System, Paris, France; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; AP-HP, Hôpital Necker Enfants-Malades, Service d'Immunologie et d'Hématologie Pédiatrique, Paris, France.
  • André-Schmutz I; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; AP-HP, Hôpital Necker Enfants-Malades, Service d'Immunologie et d'Hématologie Pédiatrique, Paris, France.
  • Lagresle-Peyrou C; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; CIC-BT 502 INSERM, Paris, France, and Département de Biothérapie, AP-HP, Hôpital Necker-Enfants Malades, Paris, France.
  • France B; INSERM UMR 1163, Laboratory of Genome Dynamics in the Immune System, Paris, France; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Kermasson L; INSERM UMR 1163, Laboratory of Genome Dynamics in the Immune System, Paris, France; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Lambert N; AP-HP, Hôpital Necker Enfants-Malades, Service d'Immunologie et d'Hématologie Pédiatrique, Paris, France; Study Center of Primary Immunodeficiencies, AP-HP, Necker Hospital, Paris, France.
  • Picard C; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; AP-HP, Hôpital Necker Enfants-Malades, Service d'Immunologie et d'Hématologie Pédiatrique, Paris, France; Study Center of Primary Immunodeficiencies, AP-HP, Necker Hospital, Paris, France.
  • Nitschke P; Service de Bioinformatique, Faculté de Médecine Pitié Salpêtrière, Paris, France.
  • Carpentier W; Plateforme Post-Génomique P3S, Faculté de Médecine Pitié Salpêtrière, Paris, France.
  • Bole-Feysot C; Plateforme de génomique, Institut Imagine, Paris, France.
  • Lim A; Institut Pasteur, Groupe Immunoscope, Département d'Immunologie, Paris, France.
  • Cavazzana M; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; Study Center of Primary Immunodeficiencies, AP-HP, Necker Hospital, Paris, France.
  • Callebaut I; CNRS UMR7590, Sorbonne Universités, Université Pierre et Marie Curie-Paris6-MNHN-IRD-IUC, Paris, France.
  • Soulier J; INSERM U944, Institut universitaire d'Hématologie, Université Denis Diderot, Paris, France.
  • Jabado N; McGill University and the Genome Quebec Innovation Centre, Montreal, Quebec, Canada.
  • Fischer A; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; AP-HP, Hôpital Necker Enfants-Malades, Service d'Immunologie et d'Hématologie Pédiatrique, Paris, France.
  • de Villartay JP; INSERM UMR 1163, Laboratory of Genome Dynamics in the Immune System, Paris, France; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Revy P; INSERM UMR 1163, Laboratory of Genome Dynamics in the Immune System, Paris, France; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France. Electronic address: patrick.revy@inserm.fr.
J Allergy Clin Immunol ; 136(6): 1619-1626.e5, 2015 Dec.
Article in En | MEDLINE | ID: mdl-26220525
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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / DNA-Binding Proteins / Immunologic Deficiency Syndromes Limits: Humans / Infant / Male Language: En Journal: J Allergy Clin Immunol Year: 2015 Type: Article Affiliation country: France
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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / DNA-Binding Proteins / Immunologic Deficiency Syndromes Limits: Humans / Infant / Male Language: En Journal: J Allergy Clin Immunol Year: 2015 Type: Article Affiliation country: France