CYP7A1-rs3808607 and APOE isoform associate with LDL cholesterol lowering after plant sterol consumption in a randomized clinical trial.

MacKay, Dylan S; Eck, Peter K; Gebauer, Sarah K; Baer, David J; Jones, Peter Jh

MacKay, Dylan S; Eck, Peter K; Gebauer, Sarah K; Baer, David J; Jones, Peter Jh.

Affiliation

MacKay DS; Richardson Centre for Functional Foods and Nutraceuticals, Department of Human Nutritional Sciences.
Eck PK; Department of Human Nutritional Sciences.
Gebauer SK; USDA, Agricultural Research Service, Beltsville Human Nutrition Research Center, Beltsville, MD, and.
Baer DJ; USDA, Agricultural Research Service, Beltsville Human Nutrition Research Center, Beltsville, MD, and.
Jones PJ; Richardson Centre for Functional Foods and Nutraceuticals, Department of Human Nutritional Sciences, Department of Food Science, University of Manitoba, Winnipeg, Canada peter.jones@umanitoba.ca.

Am J Clin Nutr ; 102(4): 951-7, 2015 Oct.

Article in En | MEDLINE | ID: mdl-26333513

Subject(s)

Apolipoproteins E/blood; Cholesterol 7-alpha-Hydroxylase/blood; Cholesterol, LDL/blood; Phytosterols/administration & dosage; Adult; Aged; Apolipoproteins E/genetics; Cholesterol/blood; Cholesterol 7-alpha-Hydroxylase/genetics; Cholesterol Ester Transfer Proteins/blood; Cholesterol Ester Transfer Proteins/genetics; Cross-Over Studies; Endpoint Determination; Female; Genetic Variation; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Single-Blind Method

Key words

LDL cholesterol; cholesterol; gene-nutrient interactions; nutrigenetics; plant sterols

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Full text: 1 Database: MEDLINE Main subject: Apolipoproteins E / Phytosterols / Cholesterol 7-alpha-Hydroxylase / Cholesterol, LDL Type of study: Clinical_trials / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Am J Clin Nutr Year: 2015 Type: Article

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