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Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
Shain, A Hunter; Garrido, Maria; Botton, Thomas; Talevich, Eric; Yeh, Iwei; Sanborn, J Zachary; Chung, Jongsuk; Wang, Nicholas J; Kakavand, Hojabr; Mann, Graham J; Thompson, John F; Wiesner, Thomas; Roy, Ritu; Olshen, Adam B; Gagnon, Alexander; Gray, Joe W; Huh, Nam; Hur, Joe S; Busam, Klaus J; Scolyer, Richard A; Cho, Raymond J; Murali, Rajmohan; Bastian, Boris C.
Affiliation
  • Shain AH; Department of Pathology, University of California, San Francisco, San Francisco, California, USA.
  • Garrido M; Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
  • Botton T; Department of Dermatology, University of California, San Francisco, San Francisco, California, USA.
  • Talevich E; Department of Pathology, University of California, San Francisco, San Francisco, California, USA.
  • Yeh I; Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
  • Sanborn JZ; Department of Dermatology, University of California, San Francisco, San Francisco, California, USA.
  • Chung J; Department of Pathology, University of California, San Francisco, San Francisco, California, USA.
  • Wang NJ; Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
  • Kakavand H; Department of Dermatology, University of California, San Francisco, San Francisco, California, USA.
  • Mann GJ; Department of Pathology, University of California, San Francisco, San Francisco, California, USA.
  • Thompson JF; Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
  • Wiesner T; Department of Dermatology, University of California, San Francisco, San Francisco, California, USA.
  • Roy R; Department of Pathology, University of California, San Francisco, San Francisco, California, USA.
  • Olshen AB; Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
  • Gagnon A; Department of Dermatology, University of California, San Francisco, San Francisco, California, USA.
  • Gray JW; Five3 Genomics, LLC, Santa Cruz, California, USA.
  • Huh N; Samsung Advanced Institute of Technology, Seoul, Korea.
  • Hur JS; Department of Biomedical Engineering, Oregon Health and Sciences University, Portland, Oregon, USA.
  • Busam KJ; Knight Cancer Institute, Oregon Health and Sciences University, Portland, Oregon, USA.
  • Scolyer RA; Melanoma Institute Australia, Sydney, New South Wales, Australia.
  • Cho RJ; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
  • Murali R; Melanoma Institute Australia, Sydney, New South Wales, Australia.
  • Bastian BC; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
Nat Genet ; 47(10): 1194-9, 2015 Oct.
Article in En | MEDLINE | ID: mdl-26343386
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Full text: 1 Database: MEDLINE Main subject: Proto-Oncogene Proteins / Promoter Regions, Genetic / MAP Kinase Signaling System / I-kappa B Proteins / Exome / Melanoma / Mutation Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2015 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Proto-Oncogene Proteins / Promoter Regions, Genetic / MAP Kinase Signaling System / I-kappa B Proteins / Exome / Melanoma / Mutation Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2015 Type: Article Affiliation country: United States