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Consequences of zygote injection and germline transfer of mutant human mitochondrial DNA in mice.
Yu, Hong; Koilkonda, Rajeshwari D; Chou, Tsung-Han; Porciatti, Vittorio; Mehta, Arpit; Hentall, Ian D; Chiodo, Vince A; Boye, Sanford L; Hauswirth, William W; Lewin, Alfred S; Guy, John.
Affiliation
  • Yu H; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami FL 33136;
  • Koilkonda RD; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami FL 33136;
  • Chou TH; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami FL 33136;
  • Porciatti V; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami FL 33136;
  • Mehta A; Hussman Institute of Human Genomics, University of Miami Miller School of Medicine, Miami, FL 33136;
  • Hentall ID; Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL 33136;
  • Chiodo VA; Department of Ophthalmology, University of Florida College of Medicine, Gainesville, FL 32603;
  • Boye SL; Department of Ophthalmology, University of Florida College of Medicine, Gainesville, FL 32603;
  • Hauswirth WW; Department of Ophthalmology, University of Florida College of Medicine, Gainesville, FL 32603;
  • Lewin AS; Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, FL 32603.
  • Guy J; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami FL 33136; jguy@med.miami.edu.
Proc Natl Acad Sci U S A ; 112(42): E5689-98, 2015 Oct 20.
Article in En | MEDLINE | ID: mdl-26438859
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Full text: 1 Database: MEDLINE Main subject: Zygote / DNA, Mitochondrial / Gene Transfer Techniques / Germ Cells / Mutation Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Zygote / DNA, Mitochondrial / Gene Transfer Techniques / Germ Cells / Mutation Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Type: Article