A feasibility study of X-ray phase-contrast mammographic tomography at the Imaging and Medical beamline of the Australian Synchrotron.
J Synchrotron Radiat
; 22(6): 1509-23, 2015 Nov.
Article
in En
| MEDLINE
| ID: mdl-26524316
ABSTRACT
Results are presented of a recent experiment at the Imaging and Medical beamline of the Australian Synchrotron intended to contribute to the implementation of low-dose high-sensitivity three-dimensional mammographic phase-contrast imaging, initially at synchrotrons and subsequently in hospitals and medical imaging clinics. The effect of such imaging parameters as X-ray energy, source size, detector resolution, sample-to-detector distance, scanning and data processing strategies in the case of propagation-based phase-contrast computed tomography (CT) have been tested, quantified, evaluated and optimized using a plastic phantom simulating relevant breast-tissue characteristics. Analysis of the data collected using a Hamamatsu CMOS Flat Panel Sensor, with a pixel size of 100 µm, revealed the presence of propagation-based phase contrast and demonstrated significant improvement of the quality of phase-contrast CT imaging compared with conventional (absorption-based) CT, at medically acceptable radiation doses.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
X-Ray Diffraction
/
Breast Neoplasms
/
Mammography
/
Image Enhancement
/
Synchrotrons
/
Imaging, Three-Dimensional
Type of study:
Diagnostic_studies
/
Evaluation_studies
Limits:
Female
/
Humans
Language:
En
Journal:
J Synchrotron Radiat
Journal subject:
RADIOLOGIA
Year:
2015
Type:
Article
Affiliation country:
Australia