Lentiviral Vector-Mediated Complementation Restored Fetal Viability but Not Placental Hyperplasia in Plac1-Deficient Mice.

Muto, Masanaga; Fujihara, Yoshitaka; Tobita, Tomohiro; Kiyozumi, Daiji; Ikawa, Masahito

Muto, Masanaga; Fujihara, Yoshitaka; Tobita, Tomohiro; Kiyozumi, Daiji; Ikawa, Masahito.

Affiliation

Muto M; Research Institute for Microbial Diseases, Osaka University, Osaka, Japan Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan.
Fujihara Y; Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Tobita T; Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Kiyozumi D; Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Ikawa M; Research Institute for Microbial Diseases, Osaka University, Osaka, Japan Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan ikawa@biken.osaka-u.ac.jp.

Biol Reprod ; 94(1): 6, 2016 Jan.

Article in En | MEDLINE | ID: mdl-26586843

Subject(s)

Fetal Viability/genetics; Lentivirus/genetics; Placenta/pathology; Pregnancy Proteins/deficiency; Pregnancy Proteins/genetics; Animals; Blastocyst/metabolism; Cell Proliferation; Female; Fetal Growth Retardation/genetics; Fetal Growth Retardation/pathology; Gene Expression Regulation, Developmental; Genetic Complementation Test; Genetic Vectors; Hyperplasia; Mice; Mice, Knockout; Nuclear Transfer Techniques; Pregnancy; Transgenes/genetics; Trophoblasts

Key words

imprinting; intrauterine growth restriction; knockout; lentiviral vector; nuclear transfer

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Full text: 1 Database: MEDLINE Main subject: Placenta / Pregnancy Proteins / Lentivirus / Fetal Viability Limits: Animals / Pregnancy Language: En Journal: Biol Reprod Year: 2016 Type: Article Affiliation country: Japan

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