Induction of WT1-specific human CD8+ T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice.

Najima, Yuho; Tomizawa-Murasawa, Mariko; Saito, Yoriko; Watanabe, Takashi; Ono, Rintaro; Ochi, Toshiki; Suzuki, Nahoko; Fujiwara, Hiroshi; Ohara, Osamu; Shultz, Leonard D; Yasukawa, Masaki; Ishikawa, Fumihiko

Najima, Yuho; Tomizawa-Murasawa, Mariko; Saito, Yoriko; Watanabe, Takashi; Ono, Rintaro; Ochi, Toshiki; Suzuki, Nahoko; Fujiwara, Hiroshi; Ohara, Osamu; Shultz, Leonard D; Yasukawa, Masaki; Ishikawa, Fumihiko.

Affiliation

Najima Y; Laboratory for Human Disease Models and.
Tomizawa-Murasawa M; Laboratory for Human Disease Models and.
Saito Y; Laboratory for Human Disease Models and.
Watanabe T; Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan;
Ono R; Laboratory for Human Disease Models and.
Ochi T; Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan; and.
Suzuki N; Laboratory for Human Disease Models and.
Fujiwara H; Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan; and.
Ohara O; Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan;
Shultz LD; The Jackson Laboratory, Bar Harbor, ME.
Yasukawa M; Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan; and.
Ishikawa F; Laboratory for Human Disease Models and.

Blood ; 127(6): 722-34, 2016 Feb 11.

Article in En | MEDLINE | ID: mdl-26702062

Subject(s)

CD8-Positive T-Lymphocytes/physiology; Cell Differentiation; HLA-A2 Antigen/genetics; HLA-A24 Antigen/genetics; Hematopoietic Stem Cells/physiology; Animals; Animals, Newborn; CD8-Positive T-Lymphocytes/metabolism; Cell Differentiation/genetics; Cell Differentiation/immunology; Cells, Cultured; Female; HLA-A2 Antigen/metabolism; HLA-A24 Antigen/metabolism; Humans; Interleukin Receptor Common gamma Subunit/genetics; K562 Cells; Mice; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; T-Lymphocytes, Cytotoxic/immunology; T-Lymphocytes, Cytotoxic/metabolism; WT1 Proteins/metabolism

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Full text: 1 Database: MEDLINE Main subject: Hematopoietic Stem Cells / HLA-A2 Antigen / Cell Differentiation / CD8-Positive T-Lymphocytes / HLA-A24 Antigen Limits: Animals / Female / Humans Language: En Journal: Blood Year: 2016 Type: Article

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