Effects of Twelve Germline Missense Variations on DNA Lesion and G-Quadruplex Bypass Activities of Human DNA Polymerase REV1.

Yeom, Mina; Kim, In-Hyeok; Kim, Jae-Kwon; Kang, KyeongJin; Eoff, Robert L; Guengerich, F Peter; Choi, Jeong-Yun

Yeom, Mina; Kim, In-Hyeok; Kim, Jae-Kwon; Kang, KyeongJin; Eoff, Robert L; Guengerich, F Peter; Choi, Jeong-Yun.

Affiliation

Eoff RL; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences , Little Rock, Arkansas 72205-7199, United States.
Guengerich FP; Department of Biochemistry, Vanderbilt University School of Medicine , Nashville, Tennessee 37232-0146, United States.

Chem Res Toxicol ; 29(3): 367-79, 2016 Mar 21.

Article in En | MEDLINE | ID: mdl-26914252

Subject(s)

DNA Damage; DNA/chemistry; DNA/metabolism; G-Quadruplexes; Germ-Line Mutation/genetics; Mutation, Missense/genetics; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; Nucleotidyltransferases/genetics; Nucleotidyltransferases/metabolism; DNA Adducts/chemistry; Humans; Models, Molecular; Nuclear Proteins/chemistry; Nucleotidyltransferases/chemistry

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Full text: 1 Database: MEDLINE Main subject: DNA Damage / DNA / Nuclear Proteins / Germ-Line Mutation / Mutation, Missense / G-Quadruplexes / Nucleotidyltransferases Limits: Humans Language: En Journal: Chem Res Toxicol Journal subject: TOXICOLOGIA Year: 2016 Type: Article

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