Differential Regulation of Bcl-xL Gene Expression by Corticosterone, Progesterone, and Retinoic Acid.

Morrissy, Steve J; Sun, Haipeng; Zhang, Jack; Strom, Joshua; Chen, Qin M

Morrissy, Steve J; Sun, Haipeng; Zhang, Jack; Strom, Joshua; Chen, Qin M.

Affiliation

Morrissy SJ; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, 85724, USA.
Sun H; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, 85724, USA.
Zhang J; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, 85724, USA.
Strom J; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, 85724, USA.
Chen QM; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, 85724, USA. qchen@email.arizona.edu.

J Biochem Mol Toxicol ; 30(6): 309-16, 2016 Jun.

Article in En | MEDLINE | ID: mdl-26915917

Subject(s)

Corticosterone/pharmacology; Gene Expression Regulation; Myocytes, Cardiac/drug effects; Progesterone/pharmacology; RNA, Messenger/genetics; Tretinoin/pharmacology; bcl-X Protein/genetics; Animals; Animals, Newborn; Antibiotics, Antineoplastic/toxicity; Apoptosis/drug effects; Apoptosis/genetics; Binding Sites; Doxorubicin/antagonists & inhibitors; Doxorubicin/toxicity; Genes, Reporter; Luciferases/genetics; Luciferases/metabolism; Myocytes, Cardiac/cytology; Myocytes, Cardiac/metabolism; NF-kappa B/genetics; NF-kappa B/metabolism; Peptide Fragments/genetics; Peptide Fragments/metabolism; Primary Cell Culture; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-jun/genetics; Proto-Oncogene Proteins c-jun/metabolism; RNA, Messenger/metabolism; Rats; Signal Transduction; Transcription Factor AP-1/genetics; Transcription Factor AP-1/metabolism; bcl-X Protein/metabolism

Key words

Apoptosis; Cell Survival; Nuclear Receptor; Retinoids; Steroids

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Full text: 1 Database: MEDLINE Main subject: Progesterone / Tretinoin / RNA, Messenger / Corticosterone / Gene Expression Regulation / Myocytes, Cardiac / Bcl-X Protein Limits: Animals Language: En Journal: J Biochem Mol Toxicol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Year: 2016 Type: Article Affiliation country: United States

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