EMT: Matter of Life or Death?
Cell
; 164(5): 840-2, 2016 Feb 25.
Article
in En
| MEDLINE
| ID: mdl-26919422
TGF-ß is long considered a "protean" cytokine in cancer, changing its role from anti- to pro-tumorigenic in a context-dependent manner. In this issue of Cell, David et al. use mouse models of pancreatic cancer to shed light on the mechanistic basis of how TGF-ß-induced EMT is coupled to either apoptosis or tumor progression.
Full text:
1
Database:
MEDLINE
Main subject:
Pancreatic Neoplasms
/
Transforming Growth Factor beta
/
Carcinoma, Ductal
/
Gene Regulatory Networks
/
Epithelial-Mesenchymal Transition
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Cell
Year:
2016
Type:
Article
Affiliation country:
United States