Bisphenol A exposure and children's behavior: A systematic review.
J Expo Sci Environ Epidemiol
; 27(2): 175-183, 2017 03.
Article
in En
| MEDLINE
| ID: mdl-26956939
ABSTRACT
Bisphenol A (BPA) is an endocrine disrupting chemical used to synthesize polycarbonate plastics and epoxy resins. Previous research suggests that exposure to it can alter children's behavior. The objective of this study is to conduct a systematic review of the existing literature, examining associations between prenatal and childhood BPA exposure and behavior in children up to 12 years of age. We searched electronic bibliographic databases (MEDLINE, PubMed, EMBASE, PsycINFO, CINAHL, and ERIC), reference lists of included articles, and conference abstracts (American Psychiatric Association, American Academy of Neurology, Pediatric Academic Societies, and International Society of Environmental Epidemiology). We included original studies reporting on the association between prenatal and childhood BPA exposure that measured BPA metabolites in urine and children's behavioral outcomes. From 2811 citations, 11 articles met our inclusion criteria. Descriptive analyses indicated that prenatal exposure to maternal BPA concentrations were related to higher levels of anxiety, depression, aggression, and hyperactivity in children. BPA exposure in childhood was associated with higher levels of anxiety, depression, hyperactivity, inattention, and conduct problems. Limited observational evidence suggests an association between both prenatal and childhood exposure to BPA and adverse behavioral outcomes in children. Prospective cohort studies are needed to clarify these associations.
Full text:
1
Database:
MEDLINE
Main subject:
Phenols
/
Prenatal Exposure Delayed Effects
/
Benzhydryl Compounds
/
Child Behavior
/
Environmental Exposure
/
Neurodevelopmental Disorders
Type of study:
Observational_studies
/
Risk_factors_studies
/
Systematic_reviews
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Pregnancy
Language:
En
Journal:
J Expo Sci Environ Epidemiol
Journal subject:
EPIDEMIOLOGIA
/
SAUDE AMBIENTAL
Year:
2017
Type:
Article
Affiliation country:
Canada