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Incorporation of Phosphonate into Benzonaphthyridine Toll-like Receptor 7 Agonists for Adsorption to Aluminum Hydroxide.
Cortez, Alex; Li, Yongkai; Miller, Andrew T; Zhang, Xiaoyue; Yue, Kathy; Maginnis, Jillian; Hampton, Janice; Hall, De Shon; Shapiro, Michael; Nayak, Bishnu; D'Oro, Ugo; Li, Chun; Skibinski, David; Mbow, M Lamine; Singh, Manmohan; O'Hagan, Derek T; Cooke, Michael P; Valiante, Nicholas M; Wu, Tom Y-H.
Affiliation
  • Cortez A; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Li Y; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Miller AT; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Zhang X; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Yue K; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Maginnis J; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Hampton J; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Hall de S; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Shapiro M; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Nayak B; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • D'Oro U; GSK Vaccines , Via Florentina, 1, 53100, Siena, Italy.
  • Li C; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Skibinski D; GSK Vaccines , Via Florentina, 1, 53100, Siena, Italy.
  • Mbow ML; GSK Vaccines , 45 Sydney Street, Cambridge, Massachusetts 02139, United States.
  • Singh M; GSK Vaccines , 45 Sydney Street, Cambridge, Massachusetts 02139, United States.
  • O'Hagan DT; GSK Vaccines , 45 Sydney Street, Cambridge, Massachusetts 02139, United States.
  • Cooke MP; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Valiante NM; GSK Vaccines , 45 Sydney Street, Cambridge, Massachusetts 02139, United States.
  • Wu TY; Genomics Institute of Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
J Med Chem ; 59(12): 5868-78, 2016 06 23.
Article in En | MEDLINE | ID: mdl-27270029
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Full text: 1 Database: MEDLINE Main subject: Toll-Like Receptor 7 / Aluminum Hydroxide / Organophosphonates / Naphthyridines Limits: Animals / Female / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2016 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Toll-Like Receptor 7 / Aluminum Hydroxide / Organophosphonates / Naphthyridines Limits: Animals / Female / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2016 Type: Article Affiliation country: United States