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Disruption of the astrocytic TNFR1-GDNF axis accelerates motor neuron degeneration and disease progression in amyotrophic lateral sclerosis.
Brambilla, Liliana; Guidotti, Giulia; Martorana, Francesca; Iyer, Anand M; Aronica, Eleonora; Valori, Chiara F; Rossi, Daniela.
Affiliation
  • Brambilla L; Laboratory for Research on Neurodegenerative Disorders, IRCCS Fondazione Salvatore Maugeri, 27100 Pavia, Italy.
  • Guidotti G; Laboratory for Research on Neurodegenerative Disorders, IRCCS Fondazione Salvatore Maugeri, 27100 Pavia, Italy.
  • Martorana F; Laboratory for Research on Neurodegenerative Disorders, IRCCS Fondazione Salvatore Maugeri, 27100 Pavia, Italy.
  • Iyer AM; Department of Pathology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
  • Aronica E; Department of Pathology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
  • Valori CF; Department of Neuropathology, German Center for Neurodegenerative Diseases (DZNE), 72076 Tübingen, Germany.
  • Rossi D; Laboratory for Research on Neurodegenerative Disorders, IRCCS Fondazione Salvatore Maugeri, 27100 Pavia, Italy, daniela.rossi@fsm.it.
Hum Mol Genet ; 25(14): 3080-3095, 2016 07 15.
Article in En | MEDLINE | ID: mdl-27288458
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Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Receptors, Tumor Necrosis Factor, Type I / Glial Cell Line-Derived Neurotrophic Factor / Amyotrophic Lateral Sclerosis / Nerve Degeneration Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2016 Type: Article Affiliation country: Italy
Search on Google
Add to My VHL
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PubMed Links

Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Receptors, Tumor Necrosis Factor, Type I / Glial Cell Line-Derived Neurotrophic Factor / Amyotrophic Lateral Sclerosis / Nerve Degeneration Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2016 Type: Article Affiliation country: Italy