A critical evaluation of the fish early-life stage toxicity test for engineered nanomaterials: experimental modifications and recommendations.

Shaw, Benjamin J; Liddle, Corin C; Windeatt, Kirsten M; Handy, Richard D

Shaw, Benjamin J; Liddle, Corin C; Windeatt, Kirsten M; Handy, Richard D.

Affiliation

Shaw BJ; Ecotoxicology Research and Innovation Centre, School of Biological Sciences, Plymouth University, Drake Circus, Plymouth, PL4 8AA, UK.
Liddle CC; Ecotoxicology Research and Innovation Centre, School of Biological Sciences, Plymouth University, Drake Circus, Plymouth, PL4 8AA, UK.
Windeatt KM; Ecotoxicology Research and Innovation Centre, School of Biological Sciences, Plymouth University, Drake Circus, Plymouth, PL4 8AA, UK.
Handy RD; Ecotoxicology Research and Innovation Centre, School of Biological Sciences, Plymouth University, Drake Circus, Plymouth, PL4 8AA, UK. rhandy@plymouth.ac.uk.

Arch Toxicol ; 90(9): 2077-2107, 2016 Sep.

Article in En | MEDLINE | ID: mdl-27318802

Subject(s)

Embryo, Nonmammalian/drug effects; Larva/drug effects; Nanostructures/toxicity; Toxicity Tests/methods; Water Pollutants, Chemical/toxicity; Zebrafish/embryology; Animals; Behavior, Animal/drug effects; Biological Assay; Dose-Response Relationship, Drug; Embryo, Nonmammalian/pathology; Equipment Design; Humans; Lethal Dose 50; Reproducibility of Results; Risk Assessment; Swimming; Time Factors; Toxicity Tests/instrumentation

Key words

Dioxide; Engineered nanomaterials; Fish; Multi-walled carbon nanotubes; OECD 210 regulatory toxicity test; Silver; Titanium

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Full text: 1 Database: MEDLINE Main subject: Water Pollutants, Chemical / Zebrafish / Toxicity Tests / Nanostructures / Embryo, Nonmammalian / Larva Type of study: Etiology_studies / Guideline / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Arch Toxicol Year: 2016 Type: Article Affiliation country: United kingdom

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