Flavonoid Glycosides and Their Derivatives from the Herbs of Scorzonera austriaca Wild.
Molecules
; 21(6)2016 Jun 21.
Article
in En
| MEDLINE
| ID: mdl-27338324
ABSTRACT
Five flavonoid glycosides and two derivatives were isolated from the herbs of Scorzonera austriaca Wild by silica gel column chromatography and preparative HPLC. Their structures were identified, using chemical and spectroscopic methods, as 5,7,4'-trihydroxyflavone 6-C-(2''-O-ß-d-glucopyranosyl ß-d-glucopyranoside) (1), 5,7,3',4'-tetrahydroxyflavone 6-C-(2''-O-ß-d-glucopyranosyl ß-d-glucopyranoside) (2), quercetin 3-O-rutinoside (3), 5,7,4'-trihydroxyflavone 6-C-ß-d-glucopyranoside (4), 3'-methoxy-5,7,4'-trihydroxyflavone 6-C-ß-d-glucopyranoside (5), 5,7,4'-trihydroxyflavone 8-C-(6''-O-trans-caffeoyl ß-d-glucopyranoside) (6), and 5,7,3',4'-tetrahydroxyflavone 8-C-(6''-O-trans-caffeoyl ß-d-glucopyranoside) (7). Compounds 6 and 7 are new flavonoid glycoside derivatives, and compounds 1-5 were isolated from the herbs of Scorzonera austriaca for the first time. Compounds 6 and 7 were also assayed for their hepatoprotective activities with rat hepatocytes in vitro.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Flavonoids
/
Scorzonera
/
Glycosides
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Molecules
Journal subject:
BIOLOGIA
Year:
2016
Type:
Article
Affiliation country:
China