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Regioselective C-H hydroxylation of omeprazole sulfide by Bacillus megaterium CYP102A1 to produce a human metabolite.
Jang, Hyun-Hee; Ryu, Sang-Hoon; Le, Thien-Kim; Doan, Tiep Thi My; Nguyen, Thi Huong Ha; Park, Ki Deok; Yim, Da-Eun; Kim, Dong-Hyun; Kang, Choong-Kyung; Ahn, Taeho; Kang, Hyung-Sik; Yun, Chul-Ho.
Affiliation
  • Jang HH; School of Biological Sciences and Technology, Chonnam National University, 77 Yongbongro, Gwangju, 61186, Republic of Korea.
  • Ryu SH; School of Biological Sciences and Technology, Chonnam National University, 77 Yongbongro, Gwangju, 61186, Republic of Korea.
  • Le TK; School of Biological Sciences and Technology, Chonnam National University, 77 Yongbongro, Gwangju, 61186, Republic of Korea.
  • Doan TT; School of Biological Sciences and Technology, Chonnam National University, 77 Yongbongro, Gwangju, 61186, Republic of Korea.
  • Nguyen TH; School of Biological Sciences and Technology, Chonnam National University, 77 Yongbongro, Gwangju, 61186, Republic of Korea.
  • Park KD; Gwangju Center, Korea Basic Science Institute, Gwangju, 61186, Republic of Korea.
  • Yim DE; Department of Pharmacology and Pharmacogenomics Center, Inje University College of Medicine, Busan, 47392, Republic of Korea.
  • Kim DH; Department of Pharmacology and Pharmacogenomics Center, Inje University College of Medicine, Busan, 47392, Republic of Korea.
  • Kang CK; Hoseo University, Asan-si, Chungcheongnam-do, 31499, Republic of Korea.
  • Ahn T; College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Republic of Korea.
  • Kang HS; School of Biological Sciences and Technology, Chonnam National University, 77 Yongbongro, Gwangju, 61186, Republic of Korea.
  • Yun CH; School of Biological Sciences and Technology, Chonnam National University, 77 Yongbongro, Gwangju, 61186, Republic of Korea. chyun@jnu.ac.kr.
Biotechnol Lett ; 39(1): 105-112, 2017 Jan.
Article in En | MEDLINE | ID: mdl-27640009
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Full text: 1 Database: MEDLINE Main subject: Bacillus megaterium / Omeprazole Limits: Humans Language: En Journal: Biotechnol Lett Year: 2017 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Bacillus megaterium / Omeprazole Limits: Humans Language: En Journal: Biotechnol Lett Year: 2017 Type: Article