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The Primary Effect on the Proteome of ARID1A-mutated Ovarian Clear Cell Carcinoma is Downregulation of the Mevalonate Pathway at the Post-transcriptional Level.
Goldman, Aaron R; Bitler, Benjamin G; Schug, Zachary; Conejo-Garcia, Jose R; Zhang, Rugang; Speicher, David W.
Affiliation
  • Goldman AR; From the ‡Molecular and Cellular Oncogenesis Program, The Wistar Institute, 3601 Spruce St., Philadelphia, Pennsylvania 19104.
  • Bitler BG; §Gene Expression and Regulation Program, The Wistar Institute, 3601 Spruce St., Philadelphia, Pennsylvania 19104.
  • Schug Z; From the ‡Molecular and Cellular Oncogenesis Program, The Wistar Institute, 3601 Spruce St., Philadelphia, Pennsylvania 19104.
  • Conejo-Garcia JR; ¶Tumor Microenvironment and Metastasis Program, The Wistar Institute, 3601 Spruce St., Philadelphia, Pennsylvania 19104.
  • Zhang R; §Gene Expression and Regulation Program, The Wistar Institute, 3601 Spruce St., Philadelphia, Pennsylvania 19104.
  • Speicher DW; From the ‡Molecular and Cellular Oncogenesis Program, The Wistar Institute, 3601 Spruce St., Philadelphia, Pennsylvania 19104; speicher@wistar.org.
Mol Cell Proteomics ; 15(11): 3348-3360, 2016 11.
Article in En | MEDLINE | ID: mdl-27654507
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Full text: 1 Database: MEDLINE Main subject: Ovarian Neoplasms / Transcription Factors / Nuclear Proteins / Down-Regulation / Adenocarcinoma, Clear Cell / Proteome / Mevalonic Acid Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Mol Cell Proteomics Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2016 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Ovarian Neoplasms / Transcription Factors / Nuclear Proteins / Down-Regulation / Adenocarcinoma, Clear Cell / Proteome / Mevalonic Acid Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Mol Cell Proteomics Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2016 Type: Article