Long-term quality of life after transoral laser microsurgery for laryngeal carcinoma.
J Surg Oncol
; 114(7): 789-795, 2016 Dec.
Article
in En
| MEDLINE
| ID: mdl-27709626
ABSTRACT
BACKGROUND AND OBJECTIVES:
Previous studies showed good short-term Quality of life (QOL) after Transoral Laser Microsurgery (TLM) for laryngeal cancer. Here, we aimed to evaluate QOL after TLM in the long-term.METHODS:
Prospective longitudinal study. Sixty-two consecutive disease-free patients were evaluated using UW-QOL v4 and SF-12 questionnaires, 1 and 5 years after TLM. Changes over time were assessed according to age, location, and tumor size. Long-term VHI-10 was also evaluated.RESULTS:
The mean follow-up time was 5.41 ± 2.02 years. No differences in the global UW-QOL score were observed between 1 and 5 years after TLM (1135.00 vs. 1127.20; P = 0.4). Activity worsened slightly in the long-term (93.03 vs. 87.70; P = 0.02). Forty-two and 58% of the patients reported that their health 1 and 5 years after treatment was much better than prior to diagnosis. Initially, 3.3% considered their health much worse, which was reduced to 1.7% at 5 years. SF-12 scores remained unchanged for both physical and mental aspects (P > 0.05). The VHI-10 was 3.81 ± 5.7 for supraglottic and 7.2 ± 9.6 for glottic tumors.CONCLUSION:
Patients treated with TLM present a very good long-term QOL. Only activity deteriorates over time, while voice and swallowing remain satisfactory in the majority of patients. J. Surg. Oncol. 2016;114789-795. © 2016 2016 Wiley Periodicals, Inc.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Quality of Life
/
Laryngeal Neoplasms
/
Minimally Invasive Surgical Procedures
/
Laser Therapy
/
Microsurgery
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Surg Oncol
Year:
2016
Type:
Article
Affiliation country:
Spain