Immunoassay interference caused by heterophilic antibodies interacting with biotin.

Vos, Michel J; Rondeel, Jan M M; Mijnhout, G Sophie; Endert, Erik

Vos, Michel J; Rondeel, Jan M M; Mijnhout, G Sophie; Endert, Erik.

Affiliation

Vos MJ; Department of Laboratory Medicine, University Medical Center Groningen, PO box 30.001, 9700 RB Groningen, The.
Rondeel JMM; Department of Clinical Chemistry, Isala hospital, Zwolle, The.
Mijnhout GS; Department of Internal Medicine, Isala hospital, Zwolle, The.
Endert E; Laboratory of Endocrinology and Radiochemistry, Department of Clinical Chemistry, Academic Medical Center, Amsterdam, The.

Clin Chem Lab Med ; 55(6): e122-e126, 2017 May 01.

Article in En | MEDLINE | ID: mdl-27754962

Subject(s)

Antibodies, Heterophile/metabolism; Biotin/metabolism; Immunoassay/standards; Adult; Antibodies, Heterophile/chemistry; Antithyroid Agents/therapeutic use; Biomarkers/blood; Biotin/chemistry; False Positive Reactions; Humans; Hyperthyroidism/drug therapy; Male; Methimazole/therapeutic use; Thyrotropin/blood; Thyroxine/blood

Key words

biotin; heterophilic antibodies; immunoassay; interference

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Full text: 1 Database: MEDLINE Main subject: Biotin / Antibodies, Heterophile / Immunoassay Limits: Adult / Humans / Male Language: En Journal: Clin Chem Lab Med Journal subject: QUIMICA CLINICA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2017 Type: Article

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