Structural and Functional Study of Apoptosis-linked Gene-2·Heme-binding Protein 2 Interactions in HIV-1 Production.

Ma, Jing; Zhang, Xianfeng; Feng, Yanbin; Zhang, Hui; Wang, Xiaojun; Zheng, Yonghui; Qiao, Wentao; Liu, Xinqi

Ma, Jing; Zhang, Xianfeng; Feng, Yanbin; Zhang, Hui; Wang, Xiaojun; Zheng, Yonghui; Qiao, Wentao; Liu, Xinqi.

Affiliation

Ma J; From the State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin 300071.
Zhang X; the Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.
Feng Y; the CAAS-Michigan State University Joint Laboratory of Innate Immunity, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, and.
Zhang H; From the State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin 300071.
Wang X; From the State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin 300071.
Zheng Y; the CAAS-Michigan State University Joint Laboratory of Innate Immunity, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, and.
Qiao W; the CAAS-Michigan State University Joint Laboratory of Innate Immunity, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, and.
Liu X; From the State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin 300071, wentaoqiao@nankai.edu.cn.

J Biol Chem ; 291(52): 26670-26685, 2016 Dec 23.

Article in En | MEDLINE | ID: mdl-27784779

Subject(s)

Apoptosis Regulatory Proteins/metabolism; Calcium-Binding Proteins/metabolism; Cell Cycle Proteins/metabolism; DNA-Binding Proteins/metabolism; Endosomal Sorting Complexes Required for Transport/metabolism; HIV Infections/metabolism; HIV-1/physiology; Hemeproteins/metabolism; Pregnancy Proteins/metabolism; Transcription Factors/metabolism; Virus Replication/physiology; Apoptosis; Apoptosis Regulatory Proteins/chemistry; Apoptosis Regulatory Proteins/genetics; Calcium-Binding Proteins/chemistry; Calcium-Binding Proteins/genetics; Cell Cycle Proteins/chemistry; Cell Cycle Proteins/genetics; Crystallization; Crystallography, X-Ray; DNA-Binding Proteins/chemistry; DNA-Binding Proteins/genetics; Endosomal Sorting Complexes Required for Transport/chemistry; Endosomal Sorting Complexes Required for Transport/genetics; HIV Infections/virology; HeLa Cells; Heme-Binding Proteins; Hemeproteins/chemistry; Hemeproteins/genetics; Humans; Pregnancy Proteins/chemistry; Pregnancy Proteins/genetics; Protein Binding; Protein Conformation; Protein Transport; Transcription Factors/chemistry; Transcription Factors/genetics

Key words

ALG-2; Gag expression; crystal structure; human immunodeficiency virus (HIV); inhibition mechanism; protein-protein interaction; transport; viral replication

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Full text: 1 Database: MEDLINE Main subject: Pregnancy Proteins / Transcription Factors / Virus Replication / Calcium-Binding Proteins / HIV Infections / HIV-1 / Cell Cycle Proteins / DNA-Binding Proteins / Apoptosis Regulatory Proteins / Endosomal Sorting Complexes Required for Transport Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2016 Type: Article

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