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Belinostat and vincristine demonstrate mutually synergistic cytotoxicity associated with mitotic arrest and inhibition of polyploidy in a preclinical model of aggressive diffuse large B cell lymphoma.
Havas, Aaron P; Rodrigues, Kameron B; Bhakta, Anvi; Demirjian, Joseph A; Hahn, Seongmin; Tran, Jack; Scavello, Margarethakay; Tula-Sanchez, Ana A; Zeng, Yi; Schmelz, Monika; Smith, Catharine L.
Affiliation
  • Havas AP; a Department of Pharmacology and Toxicology , College of Pharmacy, University of Arizona , Tucson , AZ , USA.
  • Rodrigues KB; b Cancer Biology Program , University of Arizona , Tucson , AZ , USA.
  • Bhakta A; a Department of Pharmacology and Toxicology , College of Pharmacy, University of Arizona , Tucson , AZ , USA.
  • Demirjian JA; a Department of Pharmacology and Toxicology , College of Pharmacy, University of Arizona , Tucson , AZ , USA.
  • Hahn S; a Department of Pharmacology and Toxicology , College of Pharmacy, University of Arizona , Tucson , AZ , USA.
  • Tran J; c Department of Pediatrics, Steele Children's Research Center, College of Medicine , University of Arizona , Tucson , AZ , USA.
  • Scavello M; d Department of Pathology, College of Medicine , University of Arizona , Tucson , AZ , USA.
  • Tula-Sanchez AA; a Department of Pharmacology and Toxicology , College of Pharmacy, University of Arizona , Tucson , AZ , USA.
  • Zeng Y; e Biological Chemistry Program , College of Medicine, University of Arizona , Tucson , AZ , USA.
  • Schmelz M; a Department of Pharmacology and Toxicology , College of Pharmacy, University of Arizona , Tucson , AZ , USA.
  • Smith CL; c Department of Pediatrics, Steele Children's Research Center, College of Medicine , University of Arizona , Tucson , AZ , USA.
Cancer Biol Ther ; 17(12): 1240-1252, 2016 12.
Article in En | MEDLINE | ID: mdl-27791595
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Full text: 1 Database: MEDLINE Main subject: Sulfonamides / Vincristine / Lymphoma, Large B-Cell, Diffuse / Cytotoxins / Tubulin Modulators / Histone Deacetylase Inhibitors / G2 Phase Cell Cycle Checkpoints / Hydroxamic Acids / Mitosis Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Cancer Biol Ther Journal subject: NEOPLASIAS / TERAPEUTICA Year: 2016 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Sulfonamides / Vincristine / Lymphoma, Large B-Cell, Diffuse / Cytotoxins / Tubulin Modulators / Histone Deacetylase Inhibitors / G2 Phase Cell Cycle Checkpoints / Hydroxamic Acids / Mitosis Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Cancer Biol Ther Journal subject: NEOPLASIAS / TERAPEUTICA Year: 2016 Type: Article Affiliation country: United States