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Preclinical Characterization and Human Microdose Pharmacokinetics of ITMN-8187, a Nonmacrocyclic Inhibitor of the Hepatitis C Virus NS3 Protease.
Rajagopalan, Ravi; Pan, Lin; Schaefer, Caralee; Nicholas, John; Lim, Sharlene; Misialek, Shawn; Stevens, Sarah; Hooi, Lisa; Aleskovski, Natalia; Ruhrmund, Donald; Kossen, Karl; Huang, Lea; Yap, Sophia; Beigelman, Leonid; Serebryany, Vladimir; Liu, Jyanwei; Sastry, Srikonda; Seiwert, Scott; Buckman, Brad.
Affiliation
  • Rajagopalan R; InterMune Incorporated, Brisbane, California, USA pt.ravi.r@gmail.com.
  • Pan L; InterMune Incorporated, Brisbane, California, USA.
  • Schaefer C; InterMune Incorporated, Brisbane, California, USA.
  • Nicholas J; InterMune Incorporated, Brisbane, California, USA.
  • Lim S; InterMune Incorporated, Brisbane, California, USA.
  • Misialek S; InterMune Incorporated, Brisbane, California, USA.
  • Stevens S; InterMune Incorporated, Brisbane, California, USA.
  • Hooi L; InterMune Incorporated, Brisbane, California, USA.
  • Aleskovski N; InterMune Incorporated, Brisbane, California, USA.
  • Ruhrmund D; InterMune Incorporated, Brisbane, California, USA.
  • Kossen K; InterMune Incorporated, Brisbane, California, USA.
  • Huang L; InterMune Incorporated, Brisbane, California, USA.
  • Yap S; InterMune Incorporated, Brisbane, California, USA.
  • Beigelman L; InterMune Incorporated, Brisbane, California, USA.
  • Serebryany V; InterMune Incorporated, Brisbane, California, USA.
  • Liu J; InterMune Incorporated, Brisbane, California, USA.
  • Sastry S; InterMune Incorporated, Brisbane, California, USA.
  • Seiwert S; InterMune Incorporated, Brisbane, California, USA.
  • Buckman B; InterMune Incorporated, Brisbane, California, USA.
Antimicrob Agents Chemother ; 61(1)2017 01.
Article in En | MEDLINE | ID: mdl-27795376
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Protease Inhibitors / Viral Nonstructural Proteins / Hepacivirus / Simeprevir Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Antimicrob Agents Chemother Year: 2017 Type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Protease Inhibitors / Viral Nonstructural Proteins / Hepacivirus / Simeprevir Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Antimicrob Agents Chemother Year: 2017 Type: Article Affiliation country: United States