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Critical Contribution of Tyr15 in the HIV-1 Integrase (IN) in Facilitating IN Assembly and Nonenzymatic Function through the IN Precursor Form with Reverse Transcriptase.
Takahata, Tatsuro; Takeda, Eri; Tobiume, Minoru; Tokunaga, Kenzo; Yokoyama, Masaru; Huang, Yu-Lun; Hasegawa, Atsuhiko; Shioda, Tatsuo; Sato, Hironori; Kannagi, Mari; Masuda, Takao.
Affiliation
  • Takahata T; Department of Immunotherapeutics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Takeda E; Department of Viral Infections, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
  • Tobiume M; Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.
  • Tokunaga K; Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.
  • Yokoyama M; Laboratory of Viral Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases, Tokyo, Japan.
  • Huang YL; Department of Immunotherapeutics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Hasegawa A; Department of Immunotherapeutics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Shioda T; Department of Viral Infections, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
  • Sato H; Laboratory of Viral Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases, Tokyo, Japan.
  • Kannagi M; Department of Immunotherapeutics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Masuda T; Department of Immunotherapeutics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan tmasu.impt@tmd.ac.jp.
J Virol ; 91(1)2017 Jan 01.
Article in En | MEDLINE | ID: mdl-27795445
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Full text: 1 Database: MEDLINE Main subject: Tyrosine / HIV-1 / Virus Assembly / HIV Integrase / Protein Subunits / HIV Reverse Transcriptase Language: En Journal: J Virol Year: 2017 Type: Article Affiliation country: Japan
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Full text: 1 Database: MEDLINE Main subject: Tyrosine / HIV-1 / Virus Assembly / HIV Integrase / Protein Subunits / HIV Reverse Transcriptase Language: En Journal: J Virol Year: 2017 Type: Article Affiliation country: Japan