Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways.

López-Alonso, Jorge P; Fabbretti, Attilio; Kaminishi, Tatsuya; Iturrioz, Idoia; Brandi, Letizia; Gil-Carton, David; Gualerzi, Claudio O; Fucini, Paola; Connell, Sean R

López-Alonso, Jorge P; Fabbretti, Attilio; Kaminishi, Tatsuya; Iturrioz, Idoia; Brandi, Letizia; Gil-Carton, David; Gualerzi, Claudio O; Fucini, Paola; Connell, Sean R.

Affiliation

López-Alonso JP; Structural Biology Unit, CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Bizkaia, Spain.
Fabbretti A; Laboratory of Genetics, University of Camerino, 62032 Camerino, Italy.
Kaminishi T; Structural Biology Unit, CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Bizkaia, Spain.
Iturrioz I; Structural Biology Unit, CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Bizkaia, Spain.
Brandi L; Laboratory of Genetics, University of Camerino, 62032 Camerino, Italy.
Gil-Carton D; Structural Biology Unit, CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Bizkaia, Spain.
Gualerzi CO; Laboratory of Genetics, University of Camerino, 62032 Camerino, Italy.
Fucini P; Structural Biology Unit, CIC bioGUNE, Parque Tecnológico de Bizkaia, 48160 Derio, Bizkaia, Spain.
Connell SR; IKERBASQUE, Basque Foundation for Science, 48013 Bilbao, Spain.

Nucleic Acids Res ; 45(4): 2179-2187, 2017 02 28.

Article in En | MEDLINE | ID: mdl-27986852

Subject(s)

Peptide Chain Initiation, Translational; RNA, Messenger/genetics; RNA, Transfer, Met/genetics; Ribosome Subunits, Small, Bacterial/metabolism; Binding Sites; Escherichia coli/genetics; Escherichia coli/metabolism; Eukaryotic Cells/metabolism; Models, Molecular; Molecular Conformation; Prokaryotic Initiation Factors/chemistry; Prokaryotic Initiation Factors/metabolism; Protein Biosynthesis/genetics; RNA, Messenger/chemistry; RNA, Messenger/metabolism; RNA, Transfer, Met/chemistry; RNA, Transfer, Met/metabolism; Ribosome Subunits, Large, Bacterial/chemistry; Ribosome Subunits, Large, Bacterial/metabolism; Ribosome Subunits, Small, Bacterial/chemistry

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Full text: 1 Database: MEDLINE Main subject: Peptide Chain Initiation, Translational / RNA, Messenger / RNA, Transfer, Met / Ribosome Subunits, Small, Bacterial Type of study: Prognostic_studies Language: En Journal: Nucleic Acids Res Year: 2017 Type: Article Affiliation country: Spain

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