Overexpression of ribonucleotide reductase subunit M1 protein predicts shorter survival in metastatic bladder cancer patients treated with gemcitabine-containing combination chemotherapy.

Matsumura, Nagahide; Nakamura, Yasushi; Kohjimoto, Yasuo; Nishizawa, Satoshi; Kikkawa, Kazuro; Iba, Akinori; Kodama, Yoshiki; Hara, Isao

Matsumura, Nagahide; Nakamura, Yasushi; Kohjimoto, Yasuo; Nishizawa, Satoshi; Kikkawa, Kazuro; Iba, Akinori; Kodama, Yoshiki; Hara, Isao.

Affiliation

Matsumura N; Department of Urology, Wakayama Medical University, Wakayama, Japan.
Nakamura Y; Department of Clinical Laboratory Medicine, Wakayama Medical University, Wakayama, Japan.
Kohjimoto Y; Department of Urology, Wakayama Medical University, Wakayama, Japan.
Nishizawa S; Department of Urology, Wakayama Medical University, Wakayama, Japan.
Kikkawa K; Department of Urology, Wakayama Medical University, Wakayama, Japan.
Iba A; Department of Urology, Wakayama Medical University, Wakayama, Japan.
Kodama Y; Department of Urology, Kinan Hospital, Wakayama, Japan.
Hara I; Department of Urology, Wakayama Medical University, Wakayama, Japan.

Int J Urol ; 24(3): 230-235, 2017 03.

Article in En | MEDLINE | ID: mdl-28066957

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; DNA-Binding Proteins/metabolism; Endonucleases/metabolism; Tumor Suppressor Proteins/metabolism; Urinary Bladder Neoplasms/metabolism; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor/metabolism; Cisplatin/therapeutic use; Databases, Factual; Deoxycytidine/analogs & derivatives; Deoxycytidine/therapeutic use; Female; Humans; Japan; Male; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Prognosis; Ribonucleoside Diphosphate Reductase; Survival Analysis; Urinary Bladder Neoplasms/drug therapy; Urinary Bladder Neoplasms/mortality; Gemcitabine

Key words

biomarker; bladder cancer; chemotherapy; excision repair cross complementing 1; ribonucleotide reductase subunit M1

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Full text: 1 Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Antineoplastic Combined Chemotherapy Protocols / Tumor Suppressor Proteins / DNA-Binding Proteins / Endonucleases Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Int J Urol Journal subject: UROLOGIA Year: 2017 Type: Article Affiliation country: Japan

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