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Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.
Rock, Jeremy M; Hopkins, Forrest F; Chavez, Alejandro; Diallo, Marieme; Chase, Michael R; Gerrick, Elias R; Pritchard, Justin R; Church, George M; Rubin, Eric J; Sassetti, Christopher M; Schnappinger, Dirk; Fortune, Sarah M.
Affiliation
  • Rock JM; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
  • Hopkins FF; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
  • Chavez A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Diallo M; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
  • Chase MR; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Gerrick ER; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
  • Pritchard JR; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
  • Church GM; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
  • Rubin EJ; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
  • Sassetti CM; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Schnappinger D; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Fortune SM; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
Nat Microbiol ; 2: 16274, 2017 Feb 06.
Article in En | MEDLINE | ID: mdl-28165460
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Full text: 1 Database: MEDLINE Main subject: Bacterial Proteins / Transcription, Genetic / Gene Silencing / Endonucleases / Gene Knockdown Techniques / CRISPR-Cas Systems / Mycobacterium Language: En Journal: Nat Microbiol Year: 2017 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Bacterial Proteins / Transcription, Genetic / Gene Silencing / Endonucleases / Gene Knockdown Techniques / CRISPR-Cas Systems / Mycobacterium Language: En Journal: Nat Microbiol Year: 2017 Type: Article Affiliation country: United States