Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics; Carboplatin/pharmacokinetics; Carcinoma/drug therapy; Cisplatin/pharmacokinetics; Deoxycytidine/analogs & derivatives; N-Acetylgalactosaminyltransferases/genetics; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Urinary Bladder Neoplasms/drug therapy; Urothelium/drug effects; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/adverse effects; Antineoplastic Combined Chemotherapy Protocols/blood; Carboplatin/administration & dosage; Carboplatin/adverse effects; Carcinoma/genetics; Carcinoma/pathology; Cisplatin/administration & dosage; Cisplatin/adverse effects; Cisplatin/blood; Deoxycytidine/administration & dosage; Deoxycytidine/adverse effects; Deoxycytidine/blood; Deoxycytidine/pharmacokinetics; Female; Genotype; Humans; Introns; Logistic Models; Male; Middle Aged; Models, Genetic; N-Acetylgalactosaminyltransferases/metabolism; Pharmacogenetics; Phenotype; Prospective Studies; Treatment Outcome; Urinary Bladder Neoplasms/genetics; Urinary Bladder Neoplasms/pathology; Urothelium/pathology; Gemcitabine; Polypeptide N-acetylgalactosaminyltransferase