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Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings.
Pan, Xuefang; Wang, Yanting; Lübke, Torben; Hinek, Aleksander; Pshezhetsky, Alexey V.
Affiliation
  • Pan X; Department of Medical Genetics, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, Canada.
  • Wang Y; Cardiovascular Research Program, the Hospital for Sick Children and Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada.
  • Lübke T; Department of Chemistry, Biochemistry I, Bielefeld University, Bielefeld, Germany.
  • Hinek A; Cardiovascular Research Program, the Hospital for Sick Children and Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada.
  • Pshezhetsky AV; Department of Medical Genetics, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, Canada.
PLoS One ; 12(2): e0172854, 2017.
Article in En | MEDLINE | ID: mdl-28234994
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Full text: 1 Database: MEDLINE Main subject: Skin / Carboxypeptidases / Corneal Dystrophies, Hereditary / Cathepsin A / Lysosomes Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2017 Type: Article Affiliation country: Canada
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Full text: 1 Database: MEDLINE Main subject: Skin / Carboxypeptidases / Corneal Dystrophies, Hereditary / Cathepsin A / Lysosomes Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2017 Type: Article Affiliation country: Canada