Derived neutrophil to lymphocyte ratio as a prognostic factor in patients with advanced colorectal cancer according to RAS and BRAF status: a post-hoc analysis of the MRC COIN study.

Wood, Georgina; Grenader, Tal; Nash, Stephen; Adams, Richard; Kaplan, Richard; Fisher, David; Maughan, Tim; Bridgewater, John

Wood, Georgina; Grenader, Tal; Nash, Stephen; Adams, Richard; Kaplan, Richard; Fisher, David; Maughan, Tim; Bridgewater, John.

Affiliation

Wood G; aDepartment of Oncology, University College London Hospital bCancer Research UK & UCL Cancer Trials Centre cMRC Clinical Trials Unit at UCL dUCL Cancer Institute, London, UK eInstitute of Cancer & Genetics, Cardiff University School of Medicine, Velindre Hospital, Cardiff fCRUK/MRC Oxford Institute for Radiation, Oxford, UK gOncology Institute, Shaare Zedek Medical Center, Jerusalem, Israel.

Anticancer Drugs ; 28(5): 546-550, 2017 06.

Article in En | MEDLINE | ID: mdl-28252533

Subject(s)

Colorectal Neoplasms/blood; Colorectal Neoplasms/drug therapy; Lymphocytes/pathology; Neutrophils/pathology; Proto-Oncogene Proteins B-raf/genetics; ras Proteins/genetics; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Capecitabine/administration & dosage; Cetuximab/administration & dosage; Colorectal Neoplasms/enzymology; Colorectal Neoplasms/genetics; Female; Fluorouracil/administration & dosage; Humans; Male; Middle Aged; Mutation; Organoplatinum Compounds/administration & dosage; Oxaliplatin; Young Adult

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Full text: 1 Database: MEDLINE Main subject: Lymphocytes / Colorectal Neoplasms / Ras Proteins / Proto-Oncogene Proteins B-raf / Neutrophils Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Anticancer Drugs Journal subject: ANTINEOPLASICOS Year: 2017 Type: Article Affiliation country: Israel

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