Cutting Edge: Loss of T Cell RIAM Precludes Conjugate Formation with APC and Prevents Immune-Mediated Diabetes.

Lagarrigue, Frederic; Gertler, Frank B; Ginsberg, Mark H; Cantor, Joseph M

Lagarrigue, Frederic; Gertler, Frank B; Ginsberg, Mark H; Cantor, Joseph M.

Affiliation

Lagarrigue F; Department of Medicine, University of California San Diego, La Jolla, CA 92093; and.
Gertler FB; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142.
Ginsberg MH; Department of Medicine, University of California San Diego, La Jolla, CA 92093; and.
Cantor JM; Department of Medicine, University of California San Diego, La Jolla, CA 92093; and jmcantor@ucsd.edu.

J Immunol ; 198(9): 3410-3415, 2017 05 01.

Article in En | MEDLINE | ID: mdl-28348273

Subject(s)

Adaptor Proteins, Signal Transducing/metabolism; Antigen-Presenting Cells/immunology; Diabetes Mellitus, Type 1/immunology; Lymphocyte Function-Associated Antigen-1/metabolism; Membrane Proteins/metabolism; T-Lymphocytes/immunology; Talin/metabolism; Adaptor Proteins, Signal Transducing/genetics; Adoptive Transfer; Animals; Cell Proliferation/genetics; Cells, Cultured; Cytotoxicity, Immunologic/genetics; Humans; Immunological Synapses/immunology; Membrane Proteins/genetics; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; T-Lymphocytes/transplantation

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Full text: 1 Database: MEDLINE Main subject: T-Lymphocytes / Lymphocyte Function-Associated Antigen-1 / Talin / Adaptor Proteins, Signal Transducing / Diabetes Mellitus, Type 1 / Membrane Proteins / Antigen-Presenting Cells Limits: Animals / Humans Language: En Journal: J Immunol Year: 2017 Type: Article

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