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Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival.
Katerndahl, Casey D S; Heltemes-Harris, Lynn M; Willette, Mark J L; Henzler, Christine M; Frietze, Seth; Yang, Rendong; Schjerven, Hilde; Silverstein, Kevin A T; Ramsey, Laura B; Hubbard, Gregory; Wells, Andrew D; Kuiper, Roland P; Scheijen, Blanca; van Leeuwen, Frank N; Müschen, Markus; Kornblau, Steven M; Farrar, Michael A.
Affiliation
  • Katerndahl CDS; Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.
  • Heltemes-Harris LM; Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.
  • Willette MJL; Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.
  • Henzler CM; Supercomputing Institute for Advanced Computational Research, University of Minnesota, Minneapolis, Minnesota, USA.
  • Frietze S; MLRS Department, University of Vermont, Burlington, Vermont, USA.
  • Yang R; Supercomputing Institute for Advanced Computational Research, University of Minnesota, Minneapolis, Minnesota, USA.
  • Schjerven H; Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA.
  • Silverstein KAT; Supercomputing Institute for Advanced Computational Research, University of Minnesota, Minneapolis, Minnesota, USA.
  • Ramsey LB; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Hubbard G; Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.
  • Wells AD; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania and The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Kuiper RP; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
  • Scheijen B; Laboratory of Pediatric Oncology Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.
  • van Leeuwen FN; Department of Pathology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Müschen M; Laboratory of Pediatric Oncology Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Kornblau SM; Department of Systems Biology, Beckman Research Institute and City of Hope Comprehensive Cancer Center, Pasadena, California, USA.
  • Farrar MA; Department of Leukemia, The University of Texas Maryland Anderson Cancer Center, Houston, Texas, USA.
Nat Immunol ; 18(6): 694-704, 2017 06.
Article in En | MEDLINE | ID: mdl-28369050
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Full text: 1 Database: MEDLINE Main subject: B-Lymphocytes / Gene Expression Regulation, Neoplastic / Adaptor Proteins, Signal Transducing / STAT5 Transcription Factor / Ikaros Transcription Factor / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Pre-B Cell Receptors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2017 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: B-Lymphocytes / Gene Expression Regulation, Neoplastic / Adaptor Proteins, Signal Transducing / STAT5 Transcription Factor / Ikaros Transcription Factor / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Pre-B Cell Receptors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2017 Type: Article Affiliation country: United States