Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives.

Gygli, Sebastian M; Borrell, Sonia; Trauner, Andrej; Gagneux, Sebastien

Gygli, Sebastian M; Borrell, Sonia; Trauner, Andrej; Gagneux, Sebastien.

Affiliation

Gygli SM; Swiss Tropical and Public Health Institute, Department of Medical Parasitology and Infection Biology, 4002 Basel, Switzerland.
Borrell S; University of Basel, Basel, Switzerland.
Trauner A; Swiss Tropical and Public Health Institute, Department of Medical Parasitology and Infection Biology, 4002 Basel, Switzerland.
Gagneux S; University of Basel, Basel, Switzerland.

FEMS Microbiol Rev ; 41(3): 354-373, 2017 05 01.

Article in En | MEDLINE | ID: mdl-28369307

Subject(s)

Antitubercular Agents/therapeutic use; Drug Resistance, Multiple, Bacterial/genetics; Mycobacterium tuberculosis/drug effects; Mycobacterium tuberculosis/genetics; Tuberculosis, Pulmonary/drug therapy; Antitubercular Agents/metabolism; Biological Transport/physiology; Drug Resistance, Multiple, Bacterial/physiology; Humans; Tuberculosis, Pulmonary/microbiology

Key words

Mycobacterium tuberculosis; drug resistance; epistasis; evolution; fitness; mechanisms

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Full text: 1 Database: MEDLINE Main subject: Tuberculosis, Pulmonary / Drug Resistance, Multiple, Bacterial / Mycobacterium tuberculosis / Antitubercular Agents Limits: Humans Language: En Journal: FEMS Microbiol Rev Journal subject: MICROBIOLOGIA Year: 2017 Type: Article Affiliation country: Switzerland

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