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Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis.
Thompson, George R; Blair, Janis E; Wang, Sharon; Bercovitch, Robert; Bolaris, Michael; Van Den Akker, Dane; Lopez, Rodrigo; Heidari, Arash; Catanzaro, Antonino; Cadena, Jose; Chin-Hong, Peter; Spellberg, Brad; Johnson, Royce.
Affiliation
  • Thompson GR; Department of Medical Microbiology and Immunology.
  • Blair JE; Department of Internal Medicine, Division of Infectious Diseases, University of California, Davis Medical Center.
  • Wang S; Mayo Clinic Arizona, Scottsdale.
  • Bercovitch R; Department of Internal Medicine, Division of Infectious Diseases, University of California, Davis Medical Center.
  • Bolaris M; Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of California, San Diego.
  • Van Den Akker D; Department of Internal Medicine, University of California, Los Angeles (UCLA) Medical Center.
  • Lopez R; Department of Internal Medicine, Harbor-UCLA Medical Center,Torrance.
  • Heidari A; Department of Internal Medicine, Division of Infectious Diseases, University of Texas Health Sciences Center at San Antonio.
  • Catanzaro A; David Geffen School of Medicine, University of California, Los Angeles.
  • Cadena J; Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of California, San Diego.
  • Chin-Hong P; Department of Internal Medicine, Division of Infectious Diseases, University of Texas Health Sciences Center at San Antonio.
  • Spellberg B; South Texas Veterans Health Care System, San Antonio.
  • Johnson R; Department of Internal Medicine, Division of Infectious Diseases, University of California, San Francisco.
Clin Infect Dis ; 65(2): 338-341, 2017 Jul 15.
Article in En | MEDLINE | ID: mdl-28419259
Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P = .0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.
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Full text: 1 Database: MEDLINE Main subject: Meningitis, Fungal / Coccidioidomycosis / Adrenal Cortex Hormones Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2017 Type: Article
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Meningitis, Fungal / Coccidioidomycosis / Adrenal Cortex Hormones Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2017 Type: Article