In Vitro, Ex Vivo and In Vivo Techniques to Study Neuronal Migration in the Developing Cerebral Cortex.
Brain Sci
; 7(5)2017 Apr 27.
Article
in En
| MEDLINE
| ID: mdl-28448448
ABSTRACT
Neuronal migration is a fundamental biological process that underlies proper brain development and neuronal circuit formation. In the developing cerebral cortex, distinct neuronal populations, producing excitatory, inhibitory and modulatory neurotransmitters, are generated in different germinative areas and migrate along various routes to reach their final positions within the cortex. Different technical approaches and experimental models have been adopted to study the mechanisms regulating neuronal migration in the cortex. In this review, we will discuss the most common in vitro, ex vivo and in vivo techniques to visualize and study cortical neuronal migration.
Full text:
1
Database:
MEDLINE
Language:
En
Journal:
Brain Sci
Year:
2017
Type:
Article
Affiliation country:
United kingdom