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Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal.
Yan, Kelley S; Janda, Claudia Y; Chang, Junlei; Zheng, Grace X Y; Larkin, Kathryn A; Luca, Vincent C; Chia, Luis A; Mah, Amanda T; Han, Arnold; Terry, Jessica M; Ootani, Akifumi; Roelf, Kelly; Lee, Mark; Yuan, Jenny; Li, Xiao; Bolen, Christopher R; Wilhelmy, Julie; Davies, Paige S; Ueno, Hiroo; von Furstenberg, Richard J; Belgrader, Phillip; Ziraldo, Solongo B; Ordonez, Heather; Henning, Susan J; Wong, Melissa H; Snyder, Michael P; Weissman, Irving L; Hsueh, Aaron J; Mikkelsen, Tarjei S; Garcia, K Christopher; Kuo, Calvin J.
Affiliation
  • Yan KS; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Janda CY; Columbia Center for Human Development, Department of Medicine, Division of Digestive and Liver Diseases, Department of Genetics and Development, Columbia University Medical Center, New York 10032, USA.
  • Chang J; Department of Molecular and Cellular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Zheng GXY; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Larkin KA; 10x Genomics, Inc., Pleasanton, California 94566, USA.
  • Luca VC; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Chia LA; Department of Molecular and Cellular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Mah AT; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Han A; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Terry JM; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Ootani A; Columbia Center for Translational Immunology, Department of Medicine, Division of Digestive and Liver Diseases, Department of Microbiology and Immunology, Columbia University Medical Center, New York 10032, USA.
  • Roelf K; 10x Genomics, Inc., Pleasanton, California 94566, USA.
  • Lee M; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Yuan J; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Li X; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Bolen CR; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Wilhelmy J; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Davies PS; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Ueno H; Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • von Furstenberg RJ; Oregon Health &Science University, Department of Cell, Developmental and Cancer Biology, Portland, Oregon 97239, USA.
  • Belgrader P; Institute for Stem Cell Biology, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Ziraldo SB; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
  • Ordonez H; 10x Genomics, Inc., Pleasanton, California 94566, USA.
  • Henning SJ; 10x Genomics, Inc., Pleasanton, California 94566, USA.
  • Wong MH; 10x Genomics, Inc., Pleasanton, California 94566, USA.
  • Snyder MP; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
  • Weissman IL; Oregon Health &Science University, Department of Cell, Developmental and Cancer Biology, Portland, Oregon 97239, USA.
  • Hsueh AJ; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Mikkelsen TS; Institute for Stem Cell Biology, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Garcia KC; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Kuo CJ; 10x Genomics, Inc., Pleasanton, California 94566, USA.
Nature ; 545(7653): 238-242, 2017 05 11.
Article in En | MEDLINE | ID: mdl-28467820
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Full text: 1 Database: MEDLINE Main subject: Stem Cells / Thrombospondins / Receptors, G-Protein-Coupled / Wnt Proteins / Cell Self Renewal / Intestines Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2017 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Stem Cells / Thrombospondins / Receptors, G-Protein-Coupled / Wnt Proteins / Cell Self Renewal / Intestines Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2017 Type: Article Affiliation country: United States