In Vivo Molecular Bioluminescence Imaging: New Tools and Applications.
Trends Biotechnol
; 35(7): 640-652, 2017 07.
Article
in En
| MEDLINE
| ID: mdl-28501458
ABSTRACT
in vivo bioluminescence imaging (BLi) is an optical molecular imaging technique used to visualize molecular and cellular processes in health and diseases and to follow the fate of cells with high sensitivity using luciferase-based gene reporters. The high sensitivity of this technique arises from efficient photon production, followed by the reaction between luciferase enzymes and luciferin substrates. Novel discoveries and developments of luciferase reporters, substrates, and gene-editing techniques, and emerging fields of applications, promise a new era of deeper and more sensitive molecular imaging.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Molecular Imaging
/
Luminescent Measurements
Language:
En
Journal:
Trends Biotechnol
Year:
2017
Type:
Article