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An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets.
Hill, Katherine E; Kelly, Andrew D; Kuijjer, Marieke L; Barry, William; Rattani, Ahmed; Garbutt, Cassandra C; Kissick, Haydn; Janeway, Katherine; Perez-Atayde, Antonio; Goldsmith, Jeffrey; Gebhardt, Mark C; Arredouani, Mohamed S; Cote, Greg; Hornicek, Francis; Choy, Edwin; Duan, Zhenfeng; Quackenbush, John; Haibe-Kains, Benjamin; Spentzos, Dimitrios.
Affiliation
  • Hill KE; Hematology-Oncology, Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Kelly AD; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Kuijjer ML; Fels Institute for Cancer Research and Molecular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
  • Barry W; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Rattani A; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Garbutt CC; Department of Medicine, Mount Auburn Hospital, Cambridge, MA, USA.
  • Kissick H; Center for Sarcoma and Connective Tissue Oncology, Department of Orthopedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Janeway K; Department of Urology, Medical School, Emory University, Atlanta, GA, USA.
  • Perez-Atayde A; Department of Pediatric Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Goldsmith J; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Gebhardt MC; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Arredouani MS; Orthopedics, Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Cote G; Surgery, Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Hornicek F; Cancer Center, Division of Hematology and Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Choy E; Center for Sarcoma and Connective Tissue Oncology, Department of Orthopedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Duan Z; Cancer Center, Division of Hematology and Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Quackenbush J; Center for Sarcoma and Connective Tissue Oncology, Department of Orthopedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Haibe-Kains B; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Spentzos D; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
J Hematol Oncol ; 10(1): 107, 2017 05 15.
Article in En | MEDLINE | ID: mdl-28506242
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Full text: 1 Database: MEDLINE Main subject: Bone Neoplasms / Chromosomes, Human, Pair 14 / RNA, Neoplasm / Osteosarcoma / Genomic Imprinting / MicroRNAs Type of study: Prognostic_studies Limits: Humans Country/Region as subject: America do norte Language: En Journal: J Hematol Oncol Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2017 Type: Article Affiliation country: United States
Fulltext
Add to My VHL
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Full text: 1 Database: MEDLINE Main subject: Bone Neoplasms / Chromosomes, Human, Pair 14 / RNA, Neoplasm / Osteosarcoma / Genomic Imprinting / MicroRNAs Type of study: Prognostic_studies Limits: Humans Country/Region as subject: America do norte Language: En Journal: J Hematol Oncol Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2017 Type: Article Affiliation country: United States