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Antisense oligonucleotide-mediated Dnm2 knockdown prevents and reverts myotubular myopathy in mice.
Tasfaout, Hichem; Buono, Suzie; Guo, Shuling; Kretz, Christine; Messaddeq, Nadia; Booten, Sheri; Greenlee, Sarah; Monia, Brett P; Cowling, Belinda S; Laporte, Jocelyn.
Affiliation
  • Tasfaout H; Department of Translational Medicine and Neurogenetics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch 67404, France.
  • Buono S; INSERM U964, Illkirch 67404, France.
  • Guo S; CNRS UMR7104, Illkirch 67404, France.
  • Kretz C; FMTS, Strasbourg University, Illkirch 67404, France.
  • Messaddeq N; Department of Translational Medicine and Neurogenetics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch 67404, France.
  • Booten S; INSERM U964, Illkirch 67404, France.
  • Greenlee S; CNRS UMR7104, Illkirch 67404, France.
  • Monia BP; FMTS, Strasbourg University, Illkirch 67404, France.
  • Cowling BS; Ionis Pharmaceuticals Inc., Carlsbad, California 92010, USA.
  • Laporte J; Department of Translational Medicine and Neurogenetics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch 67404, France.
Nat Commun ; 8: 15661, 2017 06 07.
Article in En | MEDLINE | ID: mdl-28589938
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Full text: 1 Database: MEDLINE Main subject: Oligonucleotides, Antisense / Myopathies, Structural, Congenital / Dynamin II / Protein Tyrosine Phosphatases, Non-Receptor Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Type: Article Affiliation country: France
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Oligonucleotides, Antisense / Myopathies, Structural, Congenital / Dynamin II / Protein Tyrosine Phosphatases, Non-Receptor Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Type: Article Affiliation country: France