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Small molecule perturbation of the CAND1-Cullin1-ubiquitin cycle stabilizes p53 and triggers Epstein-Barr virus reactivation.
Tikhmyanova, Nadezhda; Tutton, Steve; Martin, Kayla A; Lu, Fang; Kossenkov, Andrew V; Paparoidamis, Nicholas; Kenney, Shannon; Salvino, Joseph M; Lieberman, Paul M.
Affiliation
  • Tikhmyanova N; The Wistar Institute, Program in Gene Expression and Regulation, Philadelphia, Pennsylvania, United States of America.
  • Tutton S; The Wistar Institute, Program in Gene Expression and Regulation, Philadelphia, Pennsylvania, United States of America.
  • Martin KA; The Wistar Institute, Program in Gene Expression and Regulation, Philadelphia, Pennsylvania, United States of America.
  • Lu F; The Wistar Institute, Program in Gene Expression and Regulation, Philadelphia, Pennsylvania, United States of America.
  • Kossenkov AV; The Wistar Institute, Program in Gene Expression and Regulation, Philadelphia, Pennsylvania, United States of America.
  • Paparoidamis N; Drexel University, College of Medicine, Department of Pharmacology, Philadelphia, Pennsylvania, United States of America.
  • Kenney S; The University of Wisconsin, School of Medicine and Public Health at Madison, McCardle Laboratory for Cancer Research, Departments of Oncology and Medicine, Madison, Wisconsin, United States of America.
  • Salvino JM; The Wistar Institute, Program in Gene Expression and Regulation, Philadelphia, Pennsylvania, United States of America.
  • Lieberman PM; Drexel University, College of Medicine, Department of Pharmacology, Philadelphia, Pennsylvania, United States of America.
PLoS Pathog ; 13(7): e1006517, 2017 Jul.
Article in En | MEDLINE | ID: mdl-28715492
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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Virus Activation / Tumor Suppressor Protein p53 / Herpesvirus 4, Human / Epstein-Barr Virus Infections / Ubiquitin / Fullerenes / Cullin Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS Pathog Year: 2017 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Virus Activation / Tumor Suppressor Protein p53 / Herpesvirus 4, Human / Epstein-Barr Virus Infections / Ubiquitin / Fullerenes / Cullin Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS Pathog Year: 2017 Type: Article Affiliation country: United States