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Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer.
Jin, Lingyan; Garcia, Jesse; Chan, Emily; de la Cruz, Cecile; Segal, Ehud; Merchant, Mark; Kharbanda, Samir; Raisner, Ryan; Haverty, Peter M; Modrusan, Zora; Ly, Justin; Choo, Edna; Kaufman, Susan; Beresini, Maureen H; Romero, F Anthony; Magnuson, Steven; Gascoigne, Karen E.
Affiliation
  • Jin L; Department of Discovery Oncology, Genentech, Inc., South San Francisco, California.
  • Garcia J; Department of Translational Oncology, Genentech, Inc., South San Francisco, California.
  • Chan E; Department of Translational Oncology, Genentech, Inc., South San Francisco, California.
  • de la Cruz C; Department of Translational Oncology, Genentech, Inc., South San Francisco, California.
  • Segal E; Department of Translational Oncology, Genentech, Inc., South San Francisco, California.
  • Merchant M; Department of Translational Oncology, Genentech, Inc., South San Francisco, California.
  • Kharbanda S; Calico Labs, South San Francisco, California.
  • Raisner R; Department of Discovery Oncology, Genentech, Inc., South San Francisco, California.
  • Haverty PM; Department of Bioinformatics, Genentech, Inc., South San Francisco, California.
  • Modrusan Z; Department of Molecular Biology, Genentech, Inc., South San Francisco, California.
  • Ly J; Department of DMPK, Genentech, Inc., South San Francisco, California.
  • Choo E; Department of DMPK, Genentech, Inc., South San Francisco, California.
  • Kaufman S; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, California.
  • Beresini MH; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, California.
  • Romero FA; Unity Biotechnology, Brisbane, California.
  • Magnuson S; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, California.
  • Gascoigne KE; Department of Discovery Oncology, Genentech, Inc., South San Francisco, California. gascoigne.karen@gene.com.
Cancer Res ; 77(20): 5564-5575, 2017 10 15.
Article in En | MEDLINE | ID: mdl-28819026
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Full text: 1 Database: MEDLINE Main subject: E1A-Associated p300 Protein / Small Molecule Libraries / Prostatic Neoplasms, Castration-Resistant Type of study: Clinical_trials / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Cancer Res Year: 2017 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: E1A-Associated p300 Protein / Small Molecule Libraries / Prostatic Neoplasms, Castration-Resistant Type of study: Clinical_trials / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Cancer Res Year: 2017 Type: Article