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Cancer Evolution Constrained by the Immune Microenvironment.
McGranahan, Nicholas; Swanton, Charles.
Affiliation
  • McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.
  • Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK. Electronic address: charles.swanton@crick.ac.uk.
Cell ; 170(5): 825-827, 2017 08 24.
Article in En | MEDLINE | ID: mdl-28841415
Tumor development is a Darwinian evolutionary process, involving the interplay between cancer subclones and the local immune microenvironment. These complex interactions are highlighted in this issue of Cell by the results from Jiménez-Sánchez et al. of a deep analysis of one patient with advanced serous carcinoma of the ovary.
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Full text: 1 Database: MEDLINE Main subject: Tumor Microenvironment / Neoplasms Limits: Female / Humans Language: En Journal: Cell Year: 2017 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Tumor Microenvironment / Neoplasms Limits: Female / Humans Language: En Journal: Cell Year: 2017 Type: Article