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A phase I study to assess the mass balance, excretion, and pharmacokinetics of [14C]-ixazomib, an oral proteasome inhibitor, in patients with advanced solid tumors.
Gupta, Neeraj; Zhang, Steven; Pusalkar, Sandeepraj; Plesescu, Mihaela; Chowdhury, Swapan; Hanley, Michael J; Wang, Bingxia; Xia, Cindy; Zhang, Xiaoquan; Venkatakrishnan, Karthik; Shepard, Dale R.
Affiliation
  • Gupta N; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, MA, 02139, USA. Neeraj.Gupta@takeda.com.
  • Zhang S; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Pusalkar S; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Plesescu M; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Chowdhury S; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Hanley MJ; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Wang B; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Xia C; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Zhang X; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Venkatakrishnan K; Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, 40 Landsdowne Street, Cambridge, MA, 02139, USA.
  • Shepard DR; Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, USA.
Invest New Drugs ; 36(3): 407-415, 2018 06.
Article in En | MEDLINE | ID: mdl-28932928
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Full text: 1 Database: MEDLINE Main subject: Boron Compounds / Carbon Radioisotopes / Proteasome Inhibitors / Glycine / Neoplasms Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Invest New Drugs Year: 2018 Type: Article Affiliation country: United States
Fulltext
Add to My VHL
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Full text: 1 Database: MEDLINE Main subject: Boron Compounds / Carbon Radioisotopes / Proteasome Inhibitors / Glycine / Neoplasms Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Invest New Drugs Year: 2018 Type: Article Affiliation country: United States