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Inhibition of hepatocyte nuclear factor 1b induces hepatic steatosis through DPP4/NOX1-mediated regulation of superoxide.
Long, Zi; Cao, Meng; Su, Shuhao; Wu, Guangyuan; Meng, Fansen; Wu, Hao; Liu, Jiangzheng; Yu, Weihua; Atabai, Kamran; Wang, Xin.
Affiliation
  • Long Z; Department of Toxicology, Shaanxi Key Lab of Free Radical Biology and Medicine, the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
  • Cao M; Department of Toxicology, Shaanxi Key Lab of Free Radical Biology and Medicine, the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
  • Su S; Department of Toxicology, Shaanxi Key Lab of Free Radical Biology and Medicine, the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
  • Wu G; Department of Toxicology, Shaanxi Key Lab of Free Radical Biology and Medicine, the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
  • Meng F; Department of Toxicology, Shaanxi Key Lab of Free Radical Biology and Medicine, the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
  • Wu H; Department of Toxicology, Shaanxi Key Lab of Free Radical Biology and Medicine, the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
  • Liu J; Department of Toxicology, Shaanxi Key Lab of Free Radical Biology and Medicine, the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
  • Yu W; Department of Toxicology, Shaanxi Key Lab of Free Radical Biology and Medicine, the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
  • Atabai K; Cardiovascular Research Institute, University of California, San Francisco, United States; Department of Medicine, University of California, San Francisco, United States.
  • Wang X; Department of Toxicology, Shaanxi Key Lab of Free Radical Biology and Medicine, the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China. Electronic address: xinwang@fmmu.ed
Free Radic Biol Med ; 113: 71-83, 2017 12.
Article in En | MEDLINE | ID: mdl-28942246
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Full text: 1 Database: MEDLINE Main subject: Superoxides / Dipeptidyl Peptidase 4 / Hepatocyte Nuclear Factor 1-beta / Non-alcoholic Fatty Liver Disease / NADPH Oxidase 1 / Liver Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Free Radic Biol Med Journal subject: BIOQUIMICA / MEDICINA Year: 2017 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Superoxides / Dipeptidyl Peptidase 4 / Hepatocyte Nuclear Factor 1-beta / Non-alcoholic Fatty Liver Disease / NADPH Oxidase 1 / Liver Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Free Radic Biol Med Journal subject: BIOQUIMICA / MEDICINA Year: 2017 Type: Article Affiliation country: China