Monocyte-Macrophages and T Cells in Atherosclerosis.

Tabas, Ira; Lichtman, Andrew H

Tabas, Ira; Lichtman, Andrew H.

Affiliation

Tabas I; Departments of Medicine, Physiology, and Pathology & Cell Biology, Columbia University Medical Center, New York, NY 10032, USA. Electronic address: iat1@columbia.edu.
Lichtman AH; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. Electronic address: alichtman@bwh.harvard.edu.

Immunity ; 47(4): 621-634, 2017 10 17.

Article in En | MEDLINE | ID: mdl-29045897

Subject(s)

Atherosclerosis/immunology; Macrophages/immunology; Monocytes/immunology; T-Lymphocytes/immunology; Adaptive Immunity/immunology; Animals; Humans; Immunity, Innate/immunology; Lipoproteins/immunology; Models, Immunological

Key words

Innate and adaptive inflammatory responses drive the progression of atherosclerosis; T cell; adaptive immunity; effector T cell; inflammation; innate immunity; macrophage; monocyte; regulatory T cell; which is the root cause of most cardiovascular disease. Tabas and Lichtman review the roles and regulation of monocyte-macrophages and T cells during the various stages of atherosclerosis and discuss how this knowledge suggests new therapeutic approaches.atherosclerosis

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Full text: 1 Database: MEDLINE Main subject: Monocytes / T-Lymphocytes / Atherosclerosis / Macrophages Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2017 Type: Article

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