Identification of a novel torque teno mini virus in cerebrospinal fluid from a child with encephalitis.
Virol Sin
; 32(6): 541-544, 2017 Dec.
Article
in En
| MEDLINE
| ID: mdl-29047018
ABSTRACT
Anelloviruses are single-strand circular DNA viruses and ubiquitous within the human population. Although there is no direct evidence, many studies have suggested the anelloviruses may be associated with a variety of diseases. In this study, a novel torque teno mini virus (TTMV) was detected in a child with unexplained encephalitis. The detected virus had a circular genome of 2943 nt in length and 3 open reading frames. It shared 45.4% - 35.9% nucleotide identities with known TTMV species and < 35% with the other species of anellovirus, which suggested it might belong to a new species within the genus Betatorquevirus. Phylogenetic analysis based on the amino acid sequences of ORF1 showed that this virus represented a distinct branch within the diversity of anellovirus. Whether this novel anellovirus strain is associated with encephalitis requires further study.
Full text:
1
Database:
MEDLINE
Main subject:
Cerebrospinal Fluid
/
Encephalitis, Viral
/
Torque teno virus
/
DNA Virus Infections
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Child, preschool
/
Humans
/
Male
Language:
En
Journal:
Virol Sin
Journal subject:
VIROLOGIA
Year:
2017
Type:
Article
Affiliation country:
China