[Ultra-high-field MRI in the Chicken Embryo in Ovo - a Model for Experimental Ophthalmology]. / Ultrahochfeld-MRT am Hühnerembryo in ovo ein Modell für die experimentelle Ophthalmologie.
Klin Monbl Augenheilkd
; 234(12): 1458-1462, 2017 Dec.
Article
in De
| MEDLINE
| ID: mdl-29145689
ABSTRACT
Ultra-high-field MRI (UHF-MRI) is an outstanding technique for non-invasive and non-destructive imaging of soft tissues and can provide versatile contrasts and high resolution in the µm range. In vivo imaging of the embryonal chick eye with its filigree anatomical structures imposes these requirements. However, due to the short embryonal development cycle, chicken are a favourite animal model for embryonal research studies. Ultra-high-field MRI allows repeated and longitudinal in ovo investigations on the same embryo. In the present study, the limitations and opportunities of in ovo MR-imaging at 7 T were evaluated and the process of eye growth was described in detail.
Full text:
1
Database:
MEDLINE
Main subject:
Ophthalmology
/
Magnetic Resonance Imaging
/
Image Enhancement
/
Models, Animal
/
Eye
Limits:
Animals
/
Humans
Language:
De
Journal:
Klin Monbl Augenheilkd
Year:
2017
Type:
Article