An adherent mucus layer attenuates the genotoxic effect of colibactin.

Reuter, Christian; Alzheimer, Mona; Walles, Heike; Oelschlaeger, Tobias A

Reuter, Christian; Alzheimer, Mona; Walles, Heike; Oelschlaeger, Tobias A.

Affiliation

Reuter C; Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany.
Alzheimer M; Department of Tissue Engineering and Regenerative Medicine (TERM), University Hospital Würzburg, Würzburg, Germany.
Walles H; Molecular Infection Biology II, Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany.
Oelschlaeger TA; Department of Tissue Engineering and Regenerative Medicine (TERM), University Hospital Würzburg, Würzburg, Germany.

Cell Microbiol ; 20(2)2018 02.

Article in En | MEDLINE | ID: mdl-29156489

Subject(s)

Gastrointestinal Tract/microbiology; Mucus/microbiology; Mutagens/metabolism; Peptides/metabolism; Polyketides/metabolism; Cell Line, Tumor; DNA Damage/physiology; Escherichia coli/pathogenicity; Gastrointestinal Microbiome/physiology; Genomic Islands/physiology; HT29 Cells; Humans; Symbiosis/physiology; Virulence/physiology

Key words

3D cell culture; Escherichia coli Nissle 1917; colibactin; genotoxin; mucin; mucus

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Full text: 1 Database: MEDLINE Main subject: Peptides / Gastrointestinal Tract / Polyketides / Mucus / Mutagens Limits: Humans Language: En Journal: Cell Microbiol Journal subject: MICROBIOLOGIA Year: 2018 Type: Article Affiliation country: Germany

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