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Derepression of the Iroquois Homeodomain Transcription Factor Gene IRX3 Confers Differentiation Block in Acute Leukemia.
Somerville, Tim D D; Simeoni, Fabrizio; Chadwick, John A; Williams, Emma L; Spencer, Gary J; Boros, Katalin; Wirth, Christopher; Tholouli, Eleni; Byers, Richard J; Somervaille, Tim C P.
Affiliation
  • Somerville TDD; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK.
  • Simeoni F; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK.
  • Chadwick JA; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK.
  • Williams EL; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK.
  • Spencer GJ; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK.
  • Boros K; Department of Histopathology, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
  • Wirth C; Applied Computational Biology and Bioinformatics Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK.
  • Tholouli E; Department of Haematology, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
  • Byers RJ; Department of Histopathology, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
  • Somervaille TCP; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK. Electronic address: tim.somervaille@cruk.manchester.ac.uk.
Cell Rep ; 22(3): 638-652, 2018 01 16.
Article in En | MEDLINE | ID: mdl-29346763

Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Leukemia, Myeloid, Acute / Homeodomain Proteins Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2018 Type: Article Affiliation country: United kingdom

Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Leukemia, Myeloid, Acute / Homeodomain Proteins Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2018 Type: Article Affiliation country: United kingdom